Abiomed Impella Platform

The Abiomed Impella platform consists of four percutaneous trans-valvular micro axial-flow acute mechanical circulatory support (AMCS) devices that provide either left or right hemodynamic support for indications of high-risk coronary intervention or cardiogenic shock. The Impella family includes: Impella 2.5, Impella CP, Impella 5.0, and Impella RP. The Impella 2.5, CP, and RP are percutaneously delivered, while Impella 5.0 requires a surgical cut-down. Like all continuous flow pumps, the fundamental principle governing the hemodynamic effect of Impella devices can be explained using the pressure head-flow (H-Q) curve where flow is directly related to rotations per minute (rpm) of the impeller and indirectly related to pressure at the inlet and outlet of the impeller. These devices work to reduce pressures and volumes within the left or right ventricle, decreasing ventricular wall stress, unloading the heart and increasing circulatory support.