The diagnostic usefulness of e-cadherin and epidermal growth factor (egf) in symptomatic gastro-esophageal reflux disease

Aims The aim of our study is to evaluate the utility of fasting E-cadherin and EGF levels in serum and saliva as a non-invasive test to predict the presence of gastro-esophageal reflux disease in patients with typical, atypical or extra-esophageal symptoms compared with healthy volunteers and to find any correlation among E-cadherin or EGF levels and patients’ characteristics, symptoms or endoscopic findings.