A comparative evaluation of renal function in inpatients taking 4l- and 1- peg-based bowel preparation: a post-hoc analysis of a multicentre prospective study

Aims Recently, a new 1-Liter polyethylene glycol (PEG) plus ascorbate bowel purge has been approved for bowel preparation (Plenvu). Concerns about the safety profile of this very-low preparation have been risen due to electrolyte shifts (in particular high serum sodium level) reported in registration trials. However, real-life data on safety profile of Plenvu are lacking. Aim of the study was to compare renal function and serum electrolytes levels in inpatients scheduled for colonoscopy prepared either with 4L- or 1L-PEG based purge.