Property of pancreatic alpha cell is modified by bone matrix osteocalcin
Proceedings for Annual Meeting of The Japanese Pharmacological Society(2019)
摘要
Osteocalcin (OC), a bone-derived protein, affects the regulation of glucose and energy homeostasis in variety of target tissues. We previously reported that the number of cells expressing GLP-1 increased in peripheral cells of mouse pancreas by long-term administration of OC, and also in isolated pancreatic islets treated with OC.
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关键词
Pancreas Development,Glucose Homeostasis
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