Proteasome and Autophagy Pathway in Corneal Epithelial Cells with Limbal Stem Cell Deficiency

Bardag-Gorce Fawzia,Lorenzo Michael Di,Niihara Robert, Sunada Sarah,Laporte Amanda,Narwani Kavita,Cortez Daileen,Stark Jeremy,Garcia Mynor,Diaz Alissa,Oliva Joan,Hoft Richard,Niihara Yutaka

International journal of ophthalmology and clinical research（2020）

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摘要

Ubiquitin proteasome pathway (UPP) failure has been reported in case of rabbit Limbal Stem Cell Deficiency (LSCD). In the present study, we examined the effect of LSCD on autophagy in comparison to LSCD's effect on UPP.

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