Japanese Herbal Medicine (Kampo) Based Antimalarial Drug Development

Introduction: Malaria is critical global health issue, especially tropical and subtropical countries. The emergence of resistance to the currently approved drug is a recurring problem thus the urgent development of new medicine with new mechanisms of action is needed. Herbal medicine is still an attractive source of the new antimalarial drug since the isolation of quinine and artemisinin. Kampo is known Japanese traditional medicine that has been used for long periods of time, and the aim of the study is to evaluate the in vitro and in vivo antimalarial activity of Kampo compounds and extracts.