CERT2 ceramide- and phospholipid-based risk score and major adverse cardiovascular events: A systematic review and meta-analysis

Andreas S Papazoglou,Nikolaos Stalikas,Dimitrios V Moysidis,Nikolaos Otountzidis,Anastasios Kartas,Efstratios Karagiannidis,George Giannakoulas,Georgios Sianos

Journal of Clinical Lipidology（2022）

引用 6|浏览8

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摘要

•Ceramides emerge as potential mediators and prognostic biomarkers of CAD.•CERT2: a novel ceramide- and phosphatidylcholine-based risk assessment score.•We meta-analyzed aggregate data of 26,896 individuals with established CAD.•CAD patients with CERT2 score >3 suffer from significantly increased risk of MACE.•CERT2: potently robust and clinically useful predictor of MACE in CAD patients

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关键词

Ceramides,CERT2,Cardiovascular disease,CVD,Lipids and Cholesterol,Prognosis,Biomarkers,Secondary Prevention

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