Irisin alleviates high glucose-induced hypertrophy in H9c2 cardiomyoblasts by inhibiting endoplasmic reticulum stress

Xiujun Li,Da-Qi Zhang,Xiaohui Wang,Qin Zhang,Liu Qian,Rongjing Song,Xuecheng Zhao,Xiuli Li

Peptides（2022）

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摘要

•Irisin reduced high glucose-induced hypertrophy in H9c2 cardiomyoblasts.•Irisin suppressed high glucose-induced oxidative stress.•Irisin reduced the expression levels of GRP78 and p-PERK/PERK.

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关键词

ANP,DCM,ERS,HG,ROS,TM,UPR

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