Impact of Cell-Free Next-Generation Sequencing on Management of Pediatric Complicated Pneumonia.

Zephyr D Dworsky, Begem Lee,Nanda Ramchandar, Tiranun Rungvivatjarus,Nicole G Coufal,John S Bradley

Hospital pediatrics（2022）

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摘要

cfNGS provided a higher diagnostic yield in our pediatric cCAP cohort compared with conventional diagnostic testing and affected management in 78% of children. Prospective studies are needed to better characterize the clinical outcome, cost-effectiveness, and antimicrobial stewardship benefits of cfNGS in pediatric cCAP.

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