Mechanistic insights into the antipruritic effects of lebrikizumab, an anti–IL-13 mAb
Journal of Allergy and Clinical Immunology(2022)
摘要
IL-13 is a potent enhancer of neuronal responses to different itch stimuli, consistent with the neuroimmune axis contributing to chronic itch-associated inflammatory skin disease, and blockade of this cytokine pathway may provide a therapeutic approach.
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关键词
IL-13,lebrikizumab,atopic dermatitis,itch
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