Visible and near-infrared optical coherence tomography (vnOCT) in normal, suspect, and glaucomatous eyes

To evaluate the clinical utility of Visible and near infrared optical coherence tomography (vnOCT) for glaucoma early detection, A total of 55 eyes from three groups of subjects (normal subjects, glaucoma suspects, glaucoma patients) were scanned by a custom-designed vnOCT device and Zeiss Spectralis OCT. The peripapillary retinal nerve fiber layer reflectivity in visible light OCT and the ratio between visible and NIR channel is more sensitive in separating suspect eyes from normal ones than clinical OCT thickness measurements. It could be a useful metric in early detection of glaucoma upon further longitudinally validation.