Experiencing the micro-world: a cell’s perspective

This talk will introduce a novel, recently developed, instrument that combines light sheet microscopy, optical trapping and multiplane imaging in a single platform capable of imaging 3D cultures of live cell over long time courses and mapping to these images the local mechanical properties of the material surrounding the cells. The presentation will highlight the wide-range of samples this instrument can study and discuss the analysis involved to evaluate the rheological properties of the material when either the trapping potential or the samples are non-isotropic.