Gene Level Data Extraction, Integration and Comparison of Preclinical Atherosclerosis Investigations in the ApoE and LDLR Knockout Mouse Models

Rachel R. Xiang,M. Elizabeth Moss, Brigett V. Carvajal,Yihua Wang,Nicholas Camarda,Alec Stepanian, Jacob Ramsey,Megan M. Shuey,Quinn Wells,Joshua A. Beckman,Iris Z. Jaffe

CIRCULATION（2021）

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摘要

Introduction: Animal models are extensively used to interrogate molecular mechanisms of disease. The apolipoprotein E knockout (ApoE-KO) and low-density lipoprotein receptor (LDLR)-KO mouse models ...

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