Abstract 12952: Endothelial Cell Specific Deletion of mTOR Ameliorates Age-Related Arterial and Metabolic Dysfunction

Torikul Islam,Shelby A Hall,Samuel I. Bloom,R. Colton Bramwell,Tavia Dutson,Jordan R. Tucker,John S. Kim,Daniel R. Machin,Anthony J. Donato,Lisa A. Lesniewski

Circulation（2021）

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摘要

Background: Systemic inhibition of mammalian target of rapamycin (mTOR) improves age-related arterial and metabolic dysfunction. Although the mechanisms and tissues involved in this amelioration re...

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endothelial cell specific deletion,metabolic dysfunction,arterial,age-related

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