Convenient one-step synthesis of alkoxy substituted pyrazine derivatives
Results in Chemistry(2021)
摘要
Abstract We report a one-step method for the synthesis of alkoxy substituted pyrazine derivatives. The process makes use of an improved acid-mediated coupling reaction to afford the products in good yields (70–90%). This method expands the scope to alkoxy substituted pyrazine structures that are poorly represented in literature.
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关键词
Pyrazine,Favipiravir,Thionyl chloride,Nucleophilic aromatic substitution
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