A pilot study to collect and integrate multi-dimensional personal air pollution exposure data: China Kadoorie Biobank (CKB)-Air study

TPS 652: Air pollution exposure modeling 2, Exhibition Hall, Ground floor, August 28, 2019, 3:00 PM - 4:30 PM Background: Many developing countries are experiencing a double burden of ambient and household air pollution (AAP, HAP). However, few previous studies have quantified personal exposure to AAP and HAP at the same time. Based on the ongoing China Kadoorie Biobank (CKB) cohort of 0.5 million Chinese adults, a pilot study was conducted to assess the feasibility of collecting and integrating multi-dimensional data to assess personal air pollution exposure. Study design: The study involved 451 participants (mean age: 58 years; 72% female) from two rural (Gansu, Henan) and one urban (Suzhou) sites of CKB, with personal exposure measurements made in warm (May–September 2017) and cool (November 2017–January 2018) seasons. In each season, each participant carried a Berkeley Air PATS+CO monitor (measuring fine particulate [PM2.5], carbon monoxide [CO], temperature, relative humidity [RH] every 10s) for 120 consecutive hours. Two additional PATS+CO were placed in the kitchen and sitting room. A TSI DustTrakTM DRX Aerosol Monitor and two in-house CAS–A1 were placed in a representative location of the survey community to capture local ambient levels of PM, nitrogen oxides, ozone, CO, temperature and RH. Participants were interviewed twice to report their 24-hour time-activity on a weekday and the weekend, and exhaled CO and blood oxygen saturation were measured. Participants also reported sociodemographics, smoking and HAP-related exposure (e.g. fuel use patterns). Emerging findings: Mixed use of clean and solid fuels was common for cooking in rural (42%) but not urban sites (0%), but most (81%) rural participants still used only solid fuels for heating. Participants spent >90% of their time indoors. Extreme peaks of PM2.5 (>1000 µg/m3) were frequently recorded in homes burning solid fuels for cooking or heating, especially in the cool season. Future work will focus on developing an integrated personal exposure model.