One-year Ageing FTIR Monitoring of PE/EVOH/PE Film after Gamma or Electron Beam Irradiation

The effects of gamma and electron beam irradiation on PE/EVOH/PE film used in biopharmaceutical and biotechnological applications were screened using Fourier Transform Infrared (FTIR) spectroscopy combined with chemometric treatment. The modifications induced by different irradiation doses (25 and 50 kGy) and different post irradiation ageing periods (1, 6 and 24 months) were studied. Results show that shortly after irradiation gamma irradiated and non-sterilized samples exhibit a different behavior than electron beam irradiated samples, whereas 6 months after irradiation gamma irradiated samples are similar to electron beam irradiated samples from a polymer arrangement point of view. (C) 2021 Elsevier Ltd. All rights reserved.