Sumoylation of the Cardiac Sodium Channel Na(V)1.5 Does Not Increase Late Sodium Current

Jin-young Yoon,Alexander Greiner, Julia Jacobs,William J. Kutschke,Young-Rae Kim,Daniel S. Matasic,Haider Mehdi,Kaikobad J. Irani,Barry London

Circulation（2021）

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摘要

Introduction: The sodium current (INa) controlling cardiac cell excitability is conducted via the Na+ channel NaV1.5 (encoded by SCN5A). Dysregulation of NaV1.5 has been implicated in arrhythmia, w...

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