Chiral pillar[n]arenes: Conformation inversion, material preparation and applications

Chiral pillar[ n ]arenes have shown great research value and application prospect in construction of chiral materials and chiral applications, due to their inherent planar chiral configurations, chiral recognition ability, easy modification and highly symmetric hydrophobic cavity. This review systematically summarized the conformation inversion factors of planar chiral pillar[5]arenes ( pR / pS ), such as solvents, temperature, substituent size, alkyl chains, chiral and achiral guest molecules. We firstly introduced the applications of chiral pillar[ n ]arenes for constructing chiral materials and pointed out that planar conformation inversion showed a great potential role in constructing chiral materials. Then, we mainly concluded the chiral applications of chiral and planar chiral pillar[ n ]arenes like chiral enantiomer analysis by circular dichroism, electrochemistry or chiral fluorescence sensing. From this review, we found that the inherent planar chiral conformation of chiral pillar[ n ]arenes have played a very important role in chiral field in the future. Conformation inversion factors of planar chiral pillar[5]arenes ( pR / pS ), such as solvents, temperature, substituent size, alkyl chains, chiral and achiral guest molecules were systematically summarized in this review. We found that planar conformation inversion plays a great potential role in construction of chiral materials. Then, we mainly introduced the chiral applications of chiral and planar chiral pillar[ n ]arenes like chiral enantiomer analysis by circular dichroism, electrochemistry or chiral fluorescence sensing. From this review we found that the inherent planar chiral conformations of chiral pillar[ n ]arenes have played a very important role in chiral field in the future.