ヒト急性骨髄性白血病細胞で活性を示す変異イソクエン酸デヒドロゲナーゼ1(R132H IDH1)のアロステリック阻害薬の発見と最適化

Jones Stuart, Ahmet Jonathan, Ayton Kelly,Ball Matthew,Cockerill Mark,Fairweather Emma,Hamilton Nicola, Harper Paul,Hitchin James,Jordan Allan,Levy Colin,Lopez Ruth, Mckenzie Eddie, Packer Martin, Plant Darren,Simpson Iain,Simpson Peter, Sinclair Ian, C P Somervaille Tim,Small Helen, J Spencer Gary, Thomson Graeme,Tonge Michael,Waddell Ian, Walsh Jarrod,Waszkowycz Bohdan, Wigglesworth Mark, H Wiseman Daniel,Ogilvie Donald

Journal of Medicinal Chemistry(2016)

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