Abstract 460: β1-Adrenergic Receptor O-glycosylation Regulates Receptor N-terminal Cleavage and Signaling Responses in Cardiomyocytes

Misun Park,Yang Kevin Xiang,G. R. Reddy,Gerd Wallukat,Susan F. Steinberg

Circulation Research（2016）

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摘要

β1-adrenergic receptors (β1ARs) mediate catecholamine actions in cardiomyocytes by coupling to both Gs/cAMP-dependent and Gs-independent/growth-regulatory pathways. Recent efforts to structurally c...

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