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A One-Pot, Multi-Component Reaction for the Synthesis of Fully Substituted 5-Amino-4-carboxamide-thiazoles.

ChemInform(2013)

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摘要
Various target compounds, intermediates in the preparation of pharmacologically active substances, are directly obtained by base-promoted condensation of 2-amido-2-cyanoacetamide (I) with a variety of aldehydes in the presence of elemental sulfur.
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关键词
synthesis,cheminform abstract,one-pot,multi-component,carboxamide-thiazoles
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