Clinical Observation of Xuebijing Injection Combined with Levofloxacin in the Treatment of Urinary Tract Infection

OBJECTIVE:To observe the clinical efficacy and safety of Xuebijing injection combined with Levofloxacin for urinary tract infection. METHODS:78 patients with urinary tract infection were randomly divided into control group(38 cases)and treatment group(40 cases). Control group was given Levofloxacin sodium chloride injection 300 mg,bid,intravenously;treatment group was given Xuebijing injection 50 ml added into 0.9% Sodium chloride injection 100 ml,bid,intravenously,within30-40 min on the basis of control group. Treatment course of 2 groups lasted for 7 days. The changes of clinical symptom and signs were observed in 2 groups before and after treatment. The urine routine,hepatic and renal function,blood routine and ADR were observed in 2 groups before and after treatment. RESULTS:Total effective rate of treatment group(82.5%)was significantly higher than control group(63.2%);there was statistical significance(P0.05). The urine routine of both groups were improved significantly;there was statistical significance(P0.05). There was no statistical significance between 2 groups after treatment(P0.05). Clinical symptom and signs of 2 groups were improved significantly;those of treatment group were improved significantly after treatment,compared with control group;there was statistical significance(P0.05). There was no statistical significance in the incidence of ADR between 2 groups(P0.05). No obvions charge was found in hepatic and renal function,blood routine of 2groups during treatment. CONCLUSIONS:Xuebijing injection combined with Levofloxacin for urinary tract infections can promote therapeutic efficacy and show good safety.