Intensity Modulated Proton Therapy for Bilateral Breast or Chest Wall and Comprehensive Nodal Irradiation for Synchronous Bilateral Breast Cancer: Initial Clinical Experience and Dosimetric Comparison

Allison E. Garda,Ashley E. Hunzeker, Ann K. Michel,Sayeh Fattahi,Satomi Shiraishi,Nicholas B. Remmes,Heather L. Schultz,W. Scott Harmsen,Dean A. Shumway,Elizabeth S. Yan,Sean S. Park,Robert W. Mutter,Kimberly S. Corbin

Advances in radiation oncology（2022）

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摘要

Bilateral breast and/or chest wall and comprehensive nodal IMPT is technically feasible and associated with low rates of severe acute toxic effects. Treatment with IMPT offered improved target coverage and normal-tissue sparing compared with photon therapy. Long-term follow-up is ongoing to assess efficacy and toxic effects.

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