Anti-obesity Effects of Artemisia annua Extract in Zucker Fatty Rats and High-Fat Diet Sprague Dawley Rats through Upregulation of Uncoupling Protein 1 (vol 30, pg 32, 2021)

Methods: We investigated the effects of water extracts of Artemisia annua (WEAA) in C3H10T1/2, a mesenchymal stem cell line, by measuring the lev -el of intracellular fat accumulation and the expression of genes associated with adipocyte differentiation. We also evaluated anti-obesity effects of WEAA in Zucker rats (male, n=15), a genetic model for the study of obesity, and in Sprague Dawley rats with high-fat diet (HFD)-induced obesity (male, n=27).