New Rat Model of Alcoholic Liver Cirrhosis Developing Acute-on-Chronic-Liver failure
Zeitschrift für Gastroenterologie38. Jahrestagung der Deutsche Arbeitsgemeinschaft zum Studium der Leber(2022)
Abstract
Introduction Acute-on-chronic liver failure (ACLF) has a dramatic 28-day mortality. Several precipitating events, such as severe alcoholic injury, bacterial translocation and infections lead via multiple organ dysfunction and failure to acute decompensation (AD) and ACLF. Validated animal models for ACLF are needed for therapeutic treatments.
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Key words
cirrhosis,rat model,acute-on-chronic-liver
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