谷歌浏览器插件
订阅小程序
在清言上使用

Graphite Sheets Modified with Poly(methylene Blue) Films: A Cost-Effective Approach for the Electrochemical Sensing of the Antibiotic Nitrofurantoin

Microchemical journal(2022)

引用 13|浏览10
暂无评分
摘要
Electroanalytical methods are suitable to quantify pharmaceutical compounds. The typically high cost for preparing many electrochemical sensors, however, has been a drawback to their widespread use. We have used inexpensive graphite sheets (GS) as conductive substrates, and modified them by electropolymerizing a film of poly(methylene blue) (PMB) by a simple, fast, and reproducible procedure based on potential cycling. The PMB film increased the sensitivity for nitrofurantoin (NFT) and provided an antifouling property to the electrode. Under optimized conditions, GS/PMB exhibited a current increase proportional to the concentration of NFT in the range of 5-100 mu mol L-1, with sensitivity and detection limit of 0.297 mu A/mu mol L-1 and 55 nmol L-1, respectively. The proposed sensor could successfully quantify NFT in tap water and urine samples. Considering the flexibility, lightweight, conductivity and surface properties of graphite sheets, and the vast number of monomers that can be electropolymerized at electrode surfaces, this approach may lead to the fabrication of several flexible, disposable, and portable devices with applications in electrochemical sensing and biosensing.
更多
查看译文
关键词
Disposable sensor,Electropolymerization,Modified sensor,Nitrofurantoin,Poly(methylene blue)
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要