Three branches involvement in retinal vein occlusion

Two patients presented with sudden painless unilateral blurry vision. The first patient was a 57-year-old female, and the second was a 71-year-old male. The medical history of the first patient was significant for diabetes mellitus and systemic hypertension. Funduscopy of both revealed an unusual form of RVO, occlusion of three main veins of the retina, with concomitant intraretinal hemorrhages, and macular edema. An extensive ischemic retina was found in the fluorescein angiography of the second patient. Retinal vein occlusion can present as three main veins occlusion in some patients due to rare anatomic variation.