Cover Feature: Formation of Supramolecular Nanostructures Through in Situ Self‐Assembly and Post‐Assembly Modification of a Biocatalytically Constructed Dipeptide Hydrazide (chem. Eur. J. 8/2022)

Thermolysin-assisted biocatalytic construction of a self-assembling dipeptide hydrazide from two kinds of non-self-assembling amino acid derivatives gives rise to the formation of supramolecular helical architectures under aqueous conditions. In addition, post-assembly modification based on hydrazone formation allows the in-situ constructed supramolecular helical architectures to be decorated with tethering hydrazide groups as chemical handles. More information can be found in the Research Article by M. Ikeda et al. (DOI: 10.1002/chem.202104421).