Suzuki–Miyaura arylation of 2,3‐, 2,4‐, 2,5‐, and 3,4‐dibromothiophenes

A convenient and general method for Suzuki-Miyaura double cross-coupling of various dibromothiophenes was developed. Using a simple and cheap catalytic system Pd(OAc)(2)/PPh3 in 95% EtOH, various (hetero)arylboronic acids react with dibromothiophenes providing diarylthiophenes, useful in the synthesis of metal-organic frameworks (MOFs), in moderate to excellent yields. The overall efficiency of the catalytic process and slight excess of boronic acids allowed to suppress formation of side products and significantly simplify the purification of products.