Association of Impaired Fasting Blood Glucose With Triple Coronary Artery Stenosis and Myocardial Infarction Among Patients With Coronary Artery Stenosis.

Chang Chen,Yequn Chen,Jiaxin Xiao, Yanhong Zhang, Zhaorui Yang,Peixuan Yang,Nan Lu,Kaihong Yi, Xiaojun Chen, Shaoxin Chen, Mary Clare O'Gara MSc,Michael O'Meara,Shu Ye,Xuerui Tan

Frontiers in cell and developmental biology(2022)

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摘要
The association between impaired fasting glucose level (IFG) and coronary heart disease (CAD) remain controversial. In the present study, we sought to ascertain a relationship of IFG with the number of diseased coronary artery and occurrence of myocardial infarction, among CAD cases. We studied 1,451 consecutive no-diabetic patients who underwent coronary angiography at the First Affiliated Hospital of Shantou University Medical College in Southern China. Demographic, biochemical, clinical and angiographic data were collected. The prevalence of IFG was higher in patients with angiographically confirmed CAD than in subjects without angiographic evidence of CAD (33.4 28.2%, = 0.034). Compared with CAD cases without IFG, CAD cases with IFG had a higher odds ratio (OR) of having triple-vessel disease as opposed to having single- or double-vessel disease [OR = 1.53, 95% confidence interval (CI) = 1.13-2.07]. Furthermore, the occurrence of MI was higher in CAD cases with IFG than in CAD cases without IFG (OR = 1.73, 95% CI = 1.27-2.36). There is an association between IFG and a predisposition to severe CAD indicated by triple vessel disease or myocardial infarction.
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coronary artery disease,impaired fasting blood glucose,myocardial infarction,single- or double-vessel disease,triple-vessel disease
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