A Review of Nitro-Hydroxylation Transformation on Aromatic Ring

Absatract: Aromatic nitro compounds are widely used as substrates to synthesize for medicine, dyes, spices, and other organic synthesis reagents for its wide sources and low cost. One of the most uses is the synthesis of phenolic compounds, the nitro group on the aromatic ring can be converted to hydroxyl after reduction, diazotization, and hydrolysis reaction, which is a traditional method to get hydroxyl. This mini-review describes the methodologies and mechanisms of nitro-hydroxylation on aromatic rings and other unique transformation methods.