Synthesis of carbon-11 radiolabelled transition metal complexes using C-11-dithiocarbamates

A novel radiolabelling method exploiting C-11-dithiocarbamate ligands has been used to generate C-11-labelled Au(i), Au(iii), Pd(ii) and Pt(ii) complexes in high radiochemical yields (71-99%). Labelled complexes were prepared in a rapid one-pot procedure via the substitution reaction of C-11-dithiocarbamate ligands with appropriate transition metal chloride precursors.