Performance assessment of the new Xpert® HIV-1 viral load XC assay for quantification of HIV-1 viral loads

Robert Ehret, Kudor Harb,Stefan Breuer,Martin Obermeier

Journal of Clinical Virology（2022）

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摘要

•Xpert HIV-1 Viral Load (VL) XC is a redesigned dual-target quantitative test.•Very high sensitivity was observed at the lower limit of detection.•The performance of the Xpert HIV-1 VL XC test matched that of the Abbott tests.•Mutations associated with integrase resistance did not impact the results.•Very good linearity and reproducibility were observed for several HIV-1 subtypes.

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关键词

Cartridge format,Dual target,HIV-1 RNA quantitative assay,Integrase mutations,Precision,Sensitivity

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