Impact of Human Papillomavirus on Wnt/Beta-Catenin Signaling in Morphological Inconspicuous Cervicovaginal Cells.

Hanife Guler Donmez,Utku Akgor,Sevgen Onder,Atakan Tanacan,Oguzhan Kuru,Nejat Ozgul,Alp Usubutun,Martin Hufbauer,Baki Akgül,Mehmet Sinan Beksac

Acta cytologica（2022）

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摘要

In conclusion, the activation of the Wnt/beta-catenin signaling pathway and upregulation of sFRP4, paralleled by an activation of the autophagic pathway may represent predisposing cellular factors early after HPV infection which need to be further determined in larger study.

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关键词

Autophagy,Beta-catenin,Human papillomavirus,Secreted frizzled-related protein 4

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