B-cell receptor dependent phagocytosis and presentation of particulate antigen by chronic lymphocytic leukemia cells.

Annabel R Minton,Lindsay D Smith,Dean J Bryant,Jonathan C Strefford,Francesco Forconi,Freda K Stevenson,David A Tumbarello,Edd James,Geir Åge Løset,Ludvig A Munthe,Andrew J Steele,Graham Packham

Exploration of targeted anti-tumor therapy（2022）

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摘要

CLL cells can internalize and present antigen from anti-IgM beads. This capacity of CLL cells may be particularly important for recruitment of T-cell help in response to particulate antigens.

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关键词

B-cell receptor,Chronic lymphocytic leukemia,T helper cell,antigen presentation,human leukocyte antigen class II,major histocompatibility complex class II,phagocytosis

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