Elevated neutralization of Omicron with sera of COVID-19 recovered and breakthrough cases vaccinated with Covaxin than two dose naïve vaccinees

Pragya D. Yadav,Gajanan N. Sapkal,Rima R. Sahay,Deepak Y. Patil,Gururaj R. Deshpande,Rajlaxmi Jain,Dimpal A. Nyayanit,Anita M. Shete,Annasaheb Suryawanshi,Ashok Nandapurkar,Yogesh K. Gurav,Priya Abraham

Journal of Infection（2022）

引用 12|浏览2

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摘要

•Neutralization of SARS-CoV-2 variants was assessed with Covaxin vaccinees.•Recovered, breakthrough cases with Covaxin demonstrated significant neutralization.•COVID naïve vaccinees has lower neutralization with Omicron.•Reduced neutralization was observed with Omicron compared to B.1, Beta, Delta.

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关键词

SARS-CoV-2,Omicron,Covaxin,Breakthrough,Neutralization,IgG antibodies

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