Epidemiological, Clinical, and Radiological Comparison of Adult and Pediatric Features in COVID-19: A Scoping Review

OBJECTIVE:To assess epidemiological, clinical, and radiological characteristics of the coronavirus disease in children and adults.METHODS:The scoping review comprised search on PubMed and Scopus Cochrane databases from January 2020 to April 2021 for English-language articles dealing with clinical and radiological manifestations amongst children and adults affected by coronavirus disease. Two reviewers independently screened the titles and abstracts.RESULTS:Of the 389 studies initially identified, 39(10%) were reviewed in detail. Data suggested that children were less frequently affected by the coronavirus disease. The affected children showed milder disease with low case fatalities compared to the adults.CONCLUSIONS:There exists significant gaps in knowledge of clinical and radiological aspects of coronavirus disease, but the available scientific data showed that the disease seems to be unusual in children.