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Development of a validated method for rapid quantification of up to sixteen cannabinoids using ultra-high-performance liquid chromatography diode-array detector with optional electrospray ionization time-of-flight mass spectrometry detection

Liguo Song,Shelby Carlson,Gabrielle Valenzuela, Madison Chao, Shashi Bhushan Pathipaka

Journal of Chromatography A(2022)

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摘要
•Development of a validated liquid chromatography diode-array detector method.•Rapid quantification of up to sixteen cannabinoids in hemp concentrates.•Recovery of sample preparation tracked in real time by spiking abnormal CBD.•Method specificity verified by time-of-flight mass spectrometry.•High contents of delta-9 THC uncovered in delta-8 THC products.
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关键词
Cannabis,Cannabinoids,Electrospray ionization time-of-flight mass spectrometry,Hemp concentrates,Ultra-high-performance liquid chromatography diode-array detector
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