Identification of potential key genes and immune infiltration in Multiple sclerosis

Multiple Sclerosis and Related Disorders(2022)

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摘要
•In clinical practice, it was found that multiple sclerosis (MS) is an extremely serious autoimmune disease of the nervous system. Currently, there are many limitations in clinical diagnosis and treatment.•Extensive evidence indicated that immune system activation plays a crucial role in the development of MS. However, the exact mechanism of MS is still not well understood.•Using bioinformatics methods, a comprehensive study of key genes and immune infiltration in MS was performed, aiming to provide new ideas and research directions for the diagnosis and treatment of MS, which may better guide clinical practice.
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关键词
Multiple sclerosis,Key genes,CIBERSORT algorithms,Immune infiltration
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