NMR spectroscopy of lipidic cubic phases

Biophysical Reviews(2021)

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摘要
Lipidic cubic phase (LCP) structures have been used for stabilisation and crystallisation of membrane proteins and show promising properties as drug carriers. In this mini-review, we present how NMR spectroscopy has played a major role in understanding the physico-chemical properties of LCPs and how recent advances in pulsed field gradient NMR techniques open new perspectives in characterising encapsulated molecules.
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关键词
Cubic phase, Encapsulation, Membrane protein, NMR, Pulsed field gradient, Diffusion
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