BRIDGE −1 TRIAL: BReak Interval Delayed surgery for Gastrointestinal Extraperitoneal rectal cancer, a multicentric phase III randomized trial

Clinical and Translational Radiation Oncology（2022）

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摘要

•The lengthening of the surgical interval has a positive impact on pathological complete response (pCR) rate.•Lengthening the surgical interval from the end of preoperative chemoradiation is not detrimental to survival outcomes in locally advanced rectal cancer.•Prospective validation of the impact of surgical interval lengthening on complete response and survival outcomes in a randomized trial.

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关键词

Rectal cancer,Surgical Interval,Neoadjuvant chemoradiotherapy,Personalized treatment

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