Cell therapy as a treatment strategy in amyotrophic lateral sclerosis

L. Moreno-Jiménez, M.S. Benito-Martín, A. Abad-Fernández,B. Selma-Calvo, N. Fernandez-Cucho,J.A. Matias-Guiu, L. Galán-Davila, A. Guerrero-Sola,U. Gómez-Pinedo,J. Matias-Guiu

Neurology Perspectives(2022)

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摘要
Cell therapy and tissue engineering are promising therapeutic strategies for such neurodegenerative diseases as amyotrophic lateral sclerosis (ALS). Studies of different cell types have reported promising yet contradictory results, and the development of biomaterials enabling the integration of exogenous and host cells has been slow. This review analyses the most promising results published to date and emphasises the need for further research into the clinical application of biomaterials.
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关键词
Stem cells,cell therapy,biomaterials,neurodegenerative diseases,ALS,Células Madre,Terapia celular,Biomateriales,Enfermedades neurodegenerativas,ELA
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