A Covalent Organic Framework with a Self-Contained Light Source for Photodynamic Therapy

Wen-Xiu Ren,Fei Kong,Yu-Qing Shao, Qing-Yun Huang, Long-Fei Sun,Jie Feng,Yu-Bin Dong

Chemical communications（2022）

引用 8|浏览9

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摘要

External light-independent antitumor PDT is successfully realized with a covalent organic framework (COF)-based host-guest nanosystem. Its highly effective antitumor behavior is fully demonstrated by both H2O2-overexpressed 4T1 and H2O2-less expressed HCT116 and MCF-7 xenograft models.

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