Improving insights into the heterogeneous HFpEF syndrome through microvascular research

Jerremy Weerts,Sanne G.J. Mourmans,Etto Eringa,Vanessa P.M. van Empel

Journal of Molecular and Cellular Cardiology（2022）

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摘要

•Microvascular dysfunction is suggested to play a crucial role in HFpEF development.•Varying microvascular alterations may resemble different HFpEF phenotypes.•Translational microvascular research could elucidate HFpEF pathophysiology.•Specific microvascular alterations in HFpEF may result in targeted interventions.

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关键词

HFpEF,Heart failure with preserved ejection fraction,Pathophysiology,Microcirculation,Microvascular dysfunction,Phenogroups,Phenotypes,Vascular biology

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