Polymorphisms of COX/PEG2 pathway-related genes are associated with the risk of lung cancer: A case–control study in China

Xiaohua Liang,Jian Wang,Yongshi Liu,Lin Wei,Feng Tian,Jianyong Sun,Guoliang Han,Yan Wang,Chao Ding,Zhaolei Guo

International Immunopharmacology（2022）

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摘要

•Rs4648298, rs2745557, rs2075797 and rs6125671 were related to an elevated risk of lung cancer.•These four SNPs were associated with risk of lung cancer in both smokers and nonsmokers.•The results provide new clues for the early detection and personalized treatment of lung cancer.

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关键词

Lung cancer,Single nucleotide polymorphisms (SNPs),PTGS2,PTGER2,PTGIS

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