Assessment of sex- and age-dependency of risk factors for intimal hyperplasia in heart transplant patients using the high resolution of optical coherence tomography

Madeleine Orban,Markus Dietl,Dominic Dischl,Patrick von Samson-Himmelstjerna, Janina Neubarth-Mayer,Anna Strüven,Anja Tengler,Andre Jakob,Marcus Fischer,Konstantinos Rizas,Tobias Petzold,Martin Orban,Daniel Braun,Jörg Hausleiter,Christian Hagl,Nikolaus A Haas,Julinda Mehilli,Robert Dalla Pozza,Steffen Massberg,Sarah Ulrich

International Journal of Cardiology（2022）

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摘要

•Cardiac allograft vasculopathy (CAV) limits survival after heart transplantation.•Intimal hyperplasia in intracoronary imaging (CAVIH) is a main determinant of CAV.•Whether the predictive value of risk factors is age- or sex-dependent is unknown.•Diabetes and dyslipidemia had a different impact on CAVIH depending on age and sex.•Total cholesterol was relevant regarding CAVIH only in women and children.

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关键词

Cardiac allograft vasculopathy,Risk factors,Sex,Pediatric patients,Adult patients,Optical coherence tomography

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