Targeted glucocorticoid analysis using ion mobility-mass spectrometry (IM-MS)

Shon P Neal, Katie M Wilson,Diana C Velosa,Christopher D Chouinard

Journal of Mass Spectrometry and Advances in the Clinical Lab（2022）

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摘要

•Liquid chromatography-ion mobility-mass spectrometry (LC-IM-MS) for glucocorticoids.•Determination of collision cross sections (CCS) for isomers.•Different cation adducts shifted mobility and improved IM separation.•Changing drift gas (He, Ar, CO2) shifted mobility and improved resolution.

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关键词

IMS,DTIMS,TWIMS,FAIMS,DMS,IM-MS,CCS,TIMS,CIMS,SLIM

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