Burden and severity of disease of aromatic L-amino acid decarboxylase deficiency: a systematic literature review.

Katharina Buesch,Rongrong Zhang, Katarzyna Szczepańska,Vladica Veličković, Lucy Turner,Milena Despotović,Branka Đorđević,Alexis Russell

Current medical research and opinion（2022）

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摘要

Irrespective of the ambulatory status of individuals, AADCd is a debilitating disease that significantly impacts quality-of-life for individuals and caregivers. It impacts the healthcare system due to the need for complex coordinated activities of a multidisciplinary specialist team.

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AADCd,ambulatory patients,disease severity,health-related quality-of-life,healthcare resource utilization,non-ambulatory patients

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