Proprotein convertase subtilisin/kexin type 9 (PCSK9) levels in primary antiphospholipid syndrome. The multicenter ATHERO-APS study

Journal of Autoimmunity(2022)

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摘要
•PCSK9 is an important risk factor for cardiovascular events.•High plasma PCSK9 levels are associated with arterial and recurrent thrombosis in patients with thrombotic PAPS.•PCSK9 should be considered as a contributing factor to thrombotic risk in PAPS.•PCSK9 inhibition may represent a secondary prevention strategy in PAPS at high thrombotic risk.
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关键词
Antiphospholipid syndrome,PCSK9,Thrombosis
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